Long standing and effective treatments for RA follow the severity of the disease, when it has been diagnosed and at what particular stage you may be relative to progression of this disease.
There are three classes of conventional treatment for rheumatoid arthritis that include fast acting drugs also known as "first-line" drugs, slower acting drugs also known as "second-line drugs and newer or "other" drugs and therapies.
First-Line Drugs
First-line drugs can include aspirin, naproxen, ibuprofen (Advil, Motrin, etc) and etodolac. These are all examples of a family of drugs called nonsteroidal anti-inflammatory drugs or, NSAIDS. NSAIDS are fast acting drugs that focus on pain, swelling and inflammation.
Your Rheumatologist may prescribe any of these drugs for you in early stages of RA or combine them with corticosteroid therapy such as cortisone injections or oral prednisone.
Second-Line Drugs
For more severe cases of RA and for rapid progression of the disease, your Rheumatologist may prescribe a second-line drug. Second-line drugs are known as 'disease-modifying anti-rheumatic drugs' or DMARDs. Some DMARDs are occasionally referred to as 'chemo' drugs because they can fall in the low-dose chemotherapy class of drugs.
Some traditional second-line drugs include Plaquenil, Azulfidine, Rheumatrex and Trexall (methotrexate), Imuran, Leukeran, and Sandimmune. These drugs also act as an immune system suppressant. A web search on any of these will give you plenty of additional information to make informed decisions.
DMARDs are slower acting, often taking weeks or months before providing any real benefit, and require careful administration by a Rheumatologist. Frequent blood work is necessary with these drugs to monitor and avoid some possible very serious side effects.
DMARDs are usually used in conjunction with first-line drugs to help with pain and inflammation.
Newer Drugs
Over the last several years a new class of RA drug therapy has been introduced called biologics. Biologics intercept a protein called the tumor necrocis factor (TNF) which is involved with the process of inflammation.
Biologics can act very quickly in reducing the symptoms of RA and many people have had excellent results using this new class of drug. Biologics are usually administered via self-injection once or twice a week.
Biologics include Enbrel, Remicade and Humira.
As with the DMARD treatments, biologics can produce some very serious side effects including a much lower immune system response, slower healing, heart and stroke issues and other serious issues.
As a side note: I was involved in an Enbrel clinical study about 4 years ago and noticed improvement after one injection. Within about 6 hours of receiving my first injection I noticed that I didn't feel like I had a low grade fever. For me, that in itself was such a relief! Unfortunately after about 4 months of treatment I had to stop due to complications with the drug.
Enbrel does work...I know this first hand. The problem with these new biologics is they are VERY expensive and many insurance companies will only cover part of the cost, if they cover the treatment at all.
Click Here for an in depth discussion of traditional treatment options by the Mayo Clinic.
Monday, August 27, 2007
Traditional Treatments For Rheumatoid Arthritis
Posted by
.
at
5:27 PM
Labels: chronic pain, rheumatoid arthritis, rheumatoid treatment
Saturday, August 25, 2007
Rheumatoid Arthritis and the Diet Connection
I found out long ago how important your diet can be in managing the symptoms of RA. When I did have flare ups, I noticed they usually happened in the morning when my stomach was feeling queasy, as if I had eaten something the previous day that didn't agree with me.
I started to keep a record of what I was eating and what effect, if any, those foods had on my RA symptoms and general well being. The current literature at the time suggested RA sufferers generally stay away from the nightshade vegetables (tomatoes, potatoes, and peppers), fried and spicy foods and some dairy products.
That is still good advice.
However what wasn't mentioned was how our bodies are all different and what can effect one person may not effect another. This usually has to do with stomach acid levels and how difficult it might be for someone to digest their food properly.
The Food Culprits
Through a long process of elimination and trial and error, here is what I found to be what I call the hot food items that really hammer me. Should I consume any foods containing the following items, I usually have very severe (joint) pain, inflammation and swelling within 30 to 45 minutes.
1. Paprika
2. Dill
3. Basil
4. MSG
5. Processed sugar
As you can imagine, a large spectrum of foods contain these items.
Paprika is a killer for me. When I started reading food ingredient labels I was shocked to see how many food items contained paprika!
Why? As far as I can tell the stuff has no flavor and does absolutely nothing to food except add some red color.
If you have rheumatoid arthritis, the next time you eat a deviled egg covered with paprika, see how you might feel in an hour or so...
I discovered the effects of dill and basil quite by accident. I love to cook and I used a lot of basil in my cooking. When I stopped cooking with basil, my overall health improved.
And tell me, who doesn't like a warm, crisp dill pickle once in awhile.
MSG was a no brainer for me since it had always caused me to have heart palpitations. However, as I got older I noticed when I consumed foods containing MSG I also had increased joint pain and inflammation .
I always suspected processed sugar could cause digestion problems. Processed sugars actually change the level of acid in your stomach usually causing those levels to drop significantly such that it is difficult for your stomach to digest ANY foods properly.
Keep a Journal of What You Eat
Food allergies are nothing new but it is especially important for rheumatoid arthritics to take control of their diets and keep a record or journal of what they consume and how those foods may effect RA symptoms. You might be surprised to find how certain foods you eat regularly can dramatically increase your joint pain levels.
I am fully convinced that diet should be one of the most important areas of focus in RA studies and it certainly deserves much attention in assisting people who suffer from this disease.
Do your homework, educate yourself and learn how your diet may have a severe impact on your RA.
Posted by
.
at
8:35 AM
Labels: chronic pain, diet, diet and rheumatoid arthritis, rheumatoid arthritis, rheumatoid pain
Tuesday, August 21, 2007
How I Control My RA
I've been the conventional therapy route. I've been the natural therapy route. I've done the mind/body/spirit exercises. I've done just about everything trying to get a handle on this disease.
Early on I was placed on the nonsteroidal anti-inflammatory drugs (NSAIDS), the corticosteroids, and the sulfa drugs. All helped a bit, given my condition wasn't too bad at the time.
Later I was placed in a clinical study involving Enbrel (a newer medication called a 'Biologic') which did help a lot but I had to stop do to a reaction to the drug and possible serious consequences.
The Rheumatologists I have seen in the past all wanted me to try the 'chemo' drugs but after much research I found those drugs to be as dangerous, if not more so, then RA itself with no guarantees that they would help much.
Today, and for the past several years, I have settled on a combination of conventional and natural therapies.
A Combination of Conventional and Natural Therapies
I take 10 mg of prednisone each day along with 800 mgs of ibuprofen, up to 3 times in a 24 hour period based on how I feel. In addition (and this is my secret weapon) I have learned how my body reacts to certain foods. So I try to watch my diet closely.
Knowing that prednisone can cause bone loss, skin problems and other issues AND too much ibuprofen can cause kidney problems, I try to supplement with vitamins, calcium, garlic, hawthorn and an occasional liver and kidney cleanse.
The above routine keeps me alive, walking and functioning within a specific set of limitations, which I have come to accept in my life.
As a side note, and no offense to all the MDs out there, I have found that most general practitioners have no clue about RA, let alone a moderate treatment plan such as this.
Unfortunately I am one of the millions of Americans who has no health insurance, so going to a Rheumatologist is simply out of the question right now. Therefore I see a GP doctor at a walk-in clinic nearby and thank god he hasn't argued with me about taking prednisone each day for several years straight. It seems if you mention prednisone to most doctors they flinch and about fall out off their chair. "Prednisone is dangerous!", they caution.
Yeah, well, so is Methotrexate as it slowly destroys your liver and lungs.
I choose the lesser of the two evils.
Finally, I have to say this. Most Rheumatologists associate themselves with allergy clinics, charge big bucks for their so-called specialized knowledge and generally have no clue about other factors that can and will influence the severity of rheumatoid arthritis. If it isn't approved by the AMA, then it is considered snake oil.
I educated the very first Rheumy I saw in the effects that certain foods can have on RA patients. At first he blew me off, but then he told me he HAD seen a pattern in his patients with the foods that I mentioned to him. He became very excited.
The next thing I knew he couldn't wait to see me to compare notes on food items I had been studying and how they can effect RA. He eventually applied my findings in his practice and he did help many of his patients. All of that, and he still charged me up to $400 a visit! Such a nice guy.
YOU are In Charge of Your Body
My point is this: Take control of YOUR medical problems. Research, learn, ask questions. Find out what works for you and what doesn't. Find out what other factors may aggravate your RA. Visit your doctor with a detailed list of questions. After all, this is your body, not his!
And remember, when you leave that doctor's office, you become an after thought. Period.
YOU are in charge of your body...not a doctor.
Proceed accordingly.
Posted by
.
at
9:48 AM
Labels: control rheumatoid arthritis, rheumatoid arthritis, rheumatoid pain


